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Channel: PHASE 3 – New Drug Approvals
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Saracatinib AZD0530 in phase 3 for Ovary Cancer,

Saracatinib NCGC00241099, cas 379231-04-6 893428-71-2 (trihydrate) N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine...

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ScinoPharm to Provide Active Pharmaceutical Ingredient 英文名称 Burixafor to...

英文名称Burixafor TG-0054 (2-{4-[6-amino-2-({[(1r,4r)-4-({[3-(cyclohexylamino)propyl]amino}methyl)cyclohexyl]methyl}amino)pyrimidin-4-yl]piperazin-1-yl}ethyl)phosphonic acid...

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Selexipag Meets Primary Endpoint in Pivitol Phase III Griphon Outcome Study...

June 16, 2014 Actelion Ltd today announced the top-line results of the pivotal Phase III GRIPHON study in 1,156 patients with pulmonary arterial hypertension (PAH) with selexipag, the first selective...

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Mast Therapeutics’ MST-188 Would Fit Well In Merck’s Drug Development Pipeline

http://seekingalpha.com/article/2283763-mast-therapeutics-mstminus-188-would-fit-well-in-mercks-drug-development-pipeline MST-188 (purified poloxamer 188)   MST-188 is an investigational agent,...

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PTC Therapeutics Initiates Confirmatory Phase 3 Clinical Trial of Translarna™...

ATALUREN PTC 124 3-[5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid    MF C15H9FN2O3 Molecular Weight 284.24 CAS Registry Number 775304-57-9 PTC Therapeutics Initiates Confirmatory Phase 3...

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Luseogliflozin, TS 071…………. strongly inhibited SGLT2 activity,

      LUSEOGLIFLOZIN, CAS 898537-18-3 An antidiabetic agent that inhibits sodium-dependent glucose cotransporter 2 (SGLT2)....

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PARP Inhibitor.. Veliparib (ABT-888) 维利帕尼

Veliparib Abbott Laboratories 2-((R)-2-Methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide CAS number:  912444-00-9 (Veliparib), 912445-05-7 (Veliparib dihydrochloride) Mechanism of Action:poly...

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Decernotinib … JAK inhibitor for the treatment of autoimmune and inflammatory...

Decernotinib     Decernotinib N2-[2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]-N-(2,2,2-trifluoroethyl)-D-isovalinamide...

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Cortendo AB: First Patient Enrolled into NormoCort Phase 3 SONICS Trial...

KETOCONAZOLE 2S 4R   ALSO   142128-57-2228850-16-6 (tartrate) (-)-cis-1-Acetyl-4-[4-[2(S)-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4(R)-ylmethoxy]phenyl]piperazine 531.431, C26 H28...

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With Persistence And Phase 3 Win, Amicus Nears First Drug Approval …….Migalastat

Migalastat hydrochloride CAS Number: 75172-81-5 hydrochloride CAS BASE….108147-54-2 ABS ROT = (+)   +53.0 ° Conc: 1 g/100mL; Solv: water ;  589.3 nm; Temp: 24 °C IN Van den Nieuwendijk, Adrianus M. C....

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Aldoxorubicin…CytRx is pouring money into R&D of cancer-fighting drugs

Aldoxorubicin, DOXO-EMCH...

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Infinity and AbbVie partner to develop and commercialise Duvelisib for...

  Duvelisib Infinity and AbbVie partner to develop and commercialise duvelisib for cancer INK 1197; IPI 145; 8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone...

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Ragaglitazar ……..Dr. Reddy’s Research Foundation

Ragaglitazar NNC-61-0029, (-) – DRF-2725, NN-622, (−)DRF 2725 cas   222834-30-2 222834-21-1 (racemate) Hyperlipidemia; Hypertriglyceridemia; Lipid metabolism disorder; Non-insulin dependent diabetes...

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DUTOGLIPTIN

Dutogliptin tartrate Syn name: 1-[N-[3(R)-Pyrrolidinyl]glycyl]pyrrolidin-2(R)-ylboronic acid L-tartrate Cas number: 890402-81-0 Molecular Formula: C14H26BN3O9 Molecular Weight: 391.18   DUTOGLIPTIN...

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DENAGLIPTIN

DENAGLIPTIN (2S,4S)-1-[(2S)-2- amino-3,3-bis(4-fluorophenyl)propionyl]-4-fluoropyrrolidine-2-carbonitrile, (2S,4S)-4-fluoro-1-[4-fluoro-beta-(4-fluorophenyl)-L-phenylalanyl]-2-pyrrolidinecarbonitrile...

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Radius Announces Positive Phase 3 Top-Line Results for Its Investigational...

Abaloparatide WALTHAM, Mass., Dec. 21, 2014 (GLOBE NEWSWIRE) — Radius Health, Inc. today announced positive top-line 18-month fracture results from the Company’s Phase 3 clinical trial (ACTIVE)...

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PDE4 Inhibitor, SB-207499, Cilomilast……….REVISTED

Cilomilast (Ariflo, SB-207,499) cas 153259-65-5 cis-{-4-cyano-4-[3- (trans-3-hydroxycyclopentyloxy)-4-methoxyphenyl]cyclohexane-l -carboxylic acid}...

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CARIPRAZINE for major depressive disorder

CARIPRAZINE CAS 839712-12-8 (free base) CAS 1083076-69-0…HYDROCLORIDE SALT trans-N-[4-[2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-N’,N’-dimethylurea...

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Entinostat

    Entinostat Also known as: ms-275, 209783-80-2, SNDX-275, MS 275, MS-27-275, SNDX 275, NSC-706995 Molecular Formula: C21H20N4O3 Molecular Weight: 376.4085 g/mol pyridin-3-ylmethyl...

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CDK Inhibitor, MK 7965, DINACICLIB, SCH 727965

CDK Inhibitor, MK 7965, DINACICLIB, SCH 727965 SCH727965, SCH-727965, CAS 779353-01-4, Tube003, Dinaciclib (USAN/INN), UNII-4V8ECV0NBQ Molecular Formula:C21H28N6O2 Molecular Weight:396.48602 g/mol...

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